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	Podcast:		UC Science Today
	Episode:		A protein that inhibits the spread of prostate cancer to bone
	Category:		Science & Medicine
	Duration:		00:01:03
	Publish Date:		2016-06-04 19:00:00
	Description:		A specific protein has been found to inhibit prostate cancer metastasis to the bone, which is where aggressive forms of the disease primarily spread. Study leader Gabriela Loots, a biomedical scientist at the Lawrence Livermore National Laboratory, collaborated with researchers from University of California campuses at Merced and Davis. "We were curious about what is it about the bone and what kinds of signals may the bone be sending out that may attract cancer cells to migrate to the bone and then form very aggressive tumors." The team found that bone cells that were deficient in a secreted bone protein called sclerostin tended to create an environment that’s attractive to cancer cells to go there and grow. One of the things that we’re interested in now is if we were to combine the antibody as a therapy, if that would potentially have some kind of beneficial outcome to these aggressive cancers that may be highly metastatic. So that would be something we’re interested in further investigating – to see can we can block metastasis?"
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