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	Podcast:		Talking Biotech Podcast
	Episode:		251 – The Bull that (probably) Sires Mostly Bulls
	Category:		Science & Medicine
	Duration:		00:38:53
	Publish Date:		2020-08-01 10:42:19
	Description:		Tweet Male cattle (bulls) convert feed calories to weight gain more efficiently than females (cows). If more bulls could be put into beef production, the process would be even more sustainable. Dr. Alison Van Eenennaam and her research team attempted a clever trick to skew the ratio of males to females in cattle offspring. Sex determination in mammals is driven mostly by a single gene on the Y chromosome. So what if this gene was duplicated elsewhere in the genome? Using CRISPR gene editing, this is exactly what they did. “Cosmo” the bull should produce 75% male offspring. Dr. Van Eenennaam talks about the gene, its mechanism of action, the process of editing a bull’s genome, and the regulatory climate around gene-edited beef. Dr. Van Eenennaam on Twitter: @Biobeef Dr. Van Eenennaam’s website here.
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