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	Podcast:		Talking Biotech Podcast
	Episode:		268 – What is an mRNA Vaccine?
	Category:		Science & Medicine
	Duration:		00:40:09
	Publish Date:		2020-11-28 10:12:55
	Description:		Tweet mRNA vaccines have recently been in the news as an exciting potential preventative of SARS-CoV2. The technology seems new, but has roots in the 1990’s and a long history of maturation, plagued by technical barriers and skepticism. However, the efficacy demonstrated in clinical trials is promising, and suggests that mRNA-based strategies may have a prominent role as vaccines and therapeutics against some of our most insidious diseases. Resources for this podcast: Hilleman 1994 – a conceptual review of the potential for mRNA vaccines, predicing many of its challenges. Kariko et al, 2005 – This paper contains information on how mRNA may be modified to limit its inherent antigenic activity. Schlake et al., 2012 – A very good primer to the history and theory of mRNA vaccine development.
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