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For Regina Ruppert, it’s not easy to separate work and home life. She and her husband, Lee, opened Serenity Valley Winery outside St. Louis in 2006. Since 2011, the winery has been run from their property in Fulton. “Never in a million years would I have dreamed of this, but the year our daughter graduated...I became an empty nester, turned 50 and had cancer all at the same time," Regina said. "And it wasn't a very good year. And my girlfriends suggested we look into doing this since my husband’s hobby was always winemaking.” That was in 2005. In 2006, based on her girlfriends’ recommendation, Regina and her husband researched wineries and opened in an O'Fallon, Missouri strip mall. "People in Missouri don't accept strip malls for wineries, and it was invisible. It was a beautiful strip mall, but it just wasn't where we needed to be,” Regina said. By 2011, their daughter had settled in Columbia, started teaching in the school of nursing, and that led Regina and her husband to start |