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Description:
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Featuring articles on sacubitril–valsartan in heart failure with preserved ejection fraction, genotype-guided use of P2Y12 inhibitors in primary PCI, signaling pathway inhibition in colorectal cancer, timely development of a mutation-specific drug, and modeling the placenta; a review article on hereditary thrombotic thrombocytopenic purpura; a case report of a woman with cardiopulmonary arrest during cesarean section; and Perspective articles on medical deferred action, on goal-concordant care, and on getting comfortable with risk. |