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Home > High Intensity Health Radio with Mike Mutzel > High Triglycerides more Problematic than High LDL Cholesterol, Science You Should Know
Podcast: High Intensity Health Radio with Mike Mutzel
Episode:

High Triglycerides more Problematic than High LDL Cholesterol, Science You Should Know
Category: Health
Duration: 00:24:55
Publish Date: 2022-07-30 16:32:38
Description:

The consensus in the medical community about the importance of low-density lipoprotein cholesterol (LDL-C) reduction is finally shifting. Ample research shows that elevated triglycerides and triglyceride-related lipoproteins are more problematic than LDL-C when it comes to the risk of heart and metabolic disease.

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Link to Video and Research: 

Time Stamps: bit.ly/3JjJTbH

0:45 Triglyceride-rich lipoprotein is a hallmark of diabetic dyslipidemia. It cannot be controlled by statins.  4:50 Remnant cholesterol is independently associated with the onset of diabetes.  5:33 Remnant lipoproteins are a consequence of lipid absorption from the GI tract.  6:50 Apo-B is on the extra cellular surface of atherogenic vLDL, IDL, LDL, and remnant lipoprotein.  7:40 HDL have the Apo-A1 protein on the extra-cellular surface.  8:35 Test your Apo-B to Apo-A1 ratio and your vLDL, LDL and remnant lipoprotein assessment.  9:15 IDL and vLDL are enriched in triglycerides and cholesterol and drive inflammatory processes. 9:45 Statins are anti-inflammatory.  10:45 Remnant lipoproteins drive metabolic disease by increasing ectopic lipid deposition.   11:35 Remnant lipoproteins induce endothelial dysfunction. 12:00 Clotting cascades can be driven by remnant lipoproteins.  13:35 Remnant lipoproteins can penetrate the arterial wall and become trapped and oxidized, creating plaque. 15:00 Remnant triglyceride rich lipoproteins are more atherogenic than LDL cholesterol. 15:50 Dietary fat composition can render lipoproteins more oxidizable.  17:00 Request the labs listed on page 1 of the Bloodwork Cheat Sheet. Do fasted labs then non-fasted lipid levels.  18:15 Lipid Load Test: if your blood triglycerides are more than 220 nanograms/ml, you have difficulty processing fats in the post meal window. 18:55 Lose weight, especially around the abdomen.  19:35 Eat a low carb diet. 20:05 Exercise regularly, both resistance training and aerobic exercise. 20:25 Statins lower triglycerides 20 to 30%. They also induce insulin resistance, which increases triglycerides. 20:55 Omega 3 fats reduce triglycerides. Test your omega 3s. 23:05 Optimal fasting triglycerides are around 60 and 70. Postprandial triglycerides should be less than 180.
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