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Scientists find lean subjects made protective antibodies after infection while obese subjects did not make protective antibodies—they made maladaptive autoantibodies instead. Researchers speculate that leptin plays a role in skewing the immune response toward autoimmunity after infection. Here's the details! Related: Save your seat in the upcoming Blood Work MasterClass Live Training RSVP Here: https://courses.highintensityhealth.com/store/hgwDdo2p Research, Images and Articles: https://bit.ly/3qsGYX6 Time Stamps: 0:00 Intro 0:09 Endemic Virus 0:59 Obese Don't Make Protective Antibodies 1:15 Obese people make autoantibodies 1:40 Leptin and Fat on Fire 2:40 Leptin exacerbates inflammation, autoimmunity 3:13 Study we're discussing 3:49 Make Americans Healthy Again 4:35 Blood Work MasterClass 5:30 Daniela Frasca, PhD: Obesity Hinders Immune System Response 6:10 Antibodies and BMI, C-Reactive Protein 6:43 Metainflammation and Inflammaging 7:15 Blood sugar and inflammation 8:13 Leptin and immunity 9:29 Summary of Study: immune tolerance breakdown 11:30 Lifestyle matters 12:30 Antibodies directed at fat tissue 12:52 Omega-6 Oils, Seed Oils & autoimmunity 13:50 Excess deaths related to heart disease on the rise 14:42 Image: CRP and autoantibodies 15:39 New study summary 16:21 Italy Research from fat cell spill over 16:58 Obesity is an autoimmune disease 17:05 Change your habits 17:47 Image: Behavior model Books and References: Tiny Habits: The Small Changes That Change Everything: https://amzn.to/3CbpvEQ Frasca, D., Reidy, L., Cray, C., Diaz, A., Romero, M., Kahl, K., & Blomberg, B. B. (2021). Influence of obesity on serum levels of SARS-CoV-2-specific antibodies in COVID-19 patients. Plos One, 16(3), e0245424–16. Frasca, D., Reidy, L., Romero, M., Diaz, A., Cray, C., Kahl, K., & Blomberg, B. B. (2021). The majority of SARS-CoV-2-specific antibodies in COVID-19 patients with obesity are autoimmune and not neutralizing. International Journal of Obesity, 1–6. |