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Description:
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Author: Aaron Lessen, MD Educational Pearls: - Progresses through distinct phases if untreated:
- Primary syphilis: frequently overlooked because initial chancre is painless.
- Secondary syphilis: viral syndrome, rash on trunk, palms, and soles.
- Latent syphilis: asymptomatic period, lasting 5-20 years.
- Tertiary syphilis: includes neurosyphilis (dementia, encephalitis, etc.) and cardiovascular syphilis (aortitis, etc).
- Treatment penicillin G 2.4 million units once for primary or secondary treatment; once weekly for 3 weeks for latent/tertiary.
References Mattei, P., Beachkofsky, T., Gilson, R., Wisco, O. Syphilis: A reemerging infection. 2012. American Family Physician., 86(5), 433-440. |