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Home > Emergency Medical Minute > Podcast 770: Xylazine
Podcast: Emergency Medical Minute
Episode:

Podcast 770: Xylazine
Category: Science & Medicine
Duration: 00:03:45
Publish Date: 2022-04-05 10:00:26
Description: Contributor: Don Stader, MD

Educational Pearls:

  • Xylazine, referred to as tranq dope colloquially, is an FDA approved animal tranquilizer that is circulating in the illicit drug markets of the northeastern United states
  • It is a powerful alpha-2 agonist, similar to clonidine, and patients with xylazine overdose may present similarly to opioid overdose
  • Naloxone will not reverse the effects of xylazine and management is supportive care
  • Withdrawal symptoms from xylazine use can be treated with clonidine

References

https://www.acep.org/tacticalem/newsroom/oct-2021/xylazine-an-emerging-adulterant/

Nunez J, DeJoseph ME, Gill JR. Xylazine, a Veterinary Tranquilizer, Detected in 42 Accidental Fentanyl Intoxication Deaths. Am J Forensic Med Pathol. 2021 Mar 1;42(1):9-11. doi: 10.1097/PAF.0000000000000622. PMID: 33031124.

Summarized by John Spartz, MS4 | Edited by Erik Verzemnieks, MD

 

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