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Home > Emergency Medical Minute > Podcast # 341: Tenecteplase vs. Alteplase
Podcast: Emergency Medical Minute
Episode:

Podcast # 341: Tenecteplase vs. Alteplase
Category: Science & Medicine
Duration: 00:03:09
Publish Date: 2018-06-13 11:00:00
Description:

Author:   Rachel Beham, PharmD

Educational Pearls:

  • Tenecteplase is more specific for fibrin and has a longer half-life than alteplase.
  • In setting of ischemic stroke, tenecteplase before thrombectomy was associated with a statistically higher incidence of reperfusion and better functional outcome than alteplase.

References

Bruce C.V. Campbell B et al (2018). Tenecteplase versus Alteplase before Thrombectomy for Ischemic Stroke. New England Journal of Medicine. 378:1573-1582
Total Play: 0

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