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Home > Cell & Gene: The Podcast > Gene Therapy for Inherited Retinal Diseases with Opus Genetics' Dr. George Magrath
Podcast: Cell & Gene: The Podcast
Episode:

Gene Therapy for Inherited Retinal Diseases with Opus Genetics' Dr. George Magrath

Category: Science & Medicine
Duration: 00:20:13
Publish Date: 2025-07-03 08:00:00
Description:

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In this episode of Cell & Gene: The Podcast, George Magrath, CEO of Opus Genetics, shares with Host, Erin Harris, how the company is advancing gene therapies for inherited retinal diseases (IRDs), with a focus on LCA5, a rare and severe form of childhood blindness. Built on the foundational science of Dr. Jean Bennett and leveraging the legacy of Luxturna, Magrath shares how Opus is developing subretinal AAV-based therapies targeting seven distinct mutations. He also explains why gene therapy is particularly well-suited to IRDs, shares compelling early clinical data, and discusses the promise of early intervention in preserving vision and enabling proper neural development. 

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