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Home > Dostcast > Insulin Expert on Insulin Resistance, Epigenetics, and Why India is a "Sick Nation" | Karan Sarin
Podcast: Dostcast
Episode:

Insulin Expert on Insulin Resistance, Epigenetics, and Why India is a "Sick Nation" | Karan Sarin
Category: Comedy
Duration: 02:08:43
Publish Date: 2025-12-23 14:30:00
Description:

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Karan Sarin is a certified metabolic health coach, a two-time startup founder, and the author of Sick Nation. He specializes in decoding the root causes of metabolic dysfunction through the lenses of history, epigenetics, and modern physiology.


In this episode, Vinamre and Karan discuss:


The historical and epigenetic roots of fat gain and insulin resistance

The science behind GLP-1 medications like Mounjaro and how they work

Critical but overlooked clinical markers for diabetes

Why South Asians face unique metabolic challenges

Practical steps to improve insulin sensitivity and long-term health


Follow Karan Sarin:

Instagram: https://www.instagram.com/sweetreactions/?hl=en


Timestamps


0:00 Coming Up

1:10 History of Famine & Health

13:54 Science Behind Fat Gain

17:16 Are Our Genes Inferior?

21:09 Are Medicines Flawed?

27:47 Insulin Resistance & GLP-1

36:09 Insulin & Blood Sugar

51:59 Undiagnosed Diabetic People

54:49 Clinical Markers for Diabetes

1:22:19 South Asians & Myostatins

1:24:09 What’s the Cure?

1:30:09 Nutrition

1:37:59 Lifestyle Changes

1:43:59 Mounjaro Experience

1:45:09 Fats Have a Branding Problem

1:54:09 Understanding & Handling Cortisol

2:02:39 Conclusion


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Vinamre Kasanaa is a writer at heart, podcaster and entrepreneur by craft.

He spends a significant part of his time reading and researching.

With over 500 podcasts under his belt, he’s interviewed everyone—from HNIs and industry leaders to everyday superheroes.


Follow Vinamre:

LinkedIn: https://www.linkedin.com/in/vinamre-kasanaa-b8524496/

Instagram: https://www.instagram.com/vinamrekasanaa/

Twitter: https://twitter.com/VinamreKasanaa


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Twitter: https://twitter.com/dostcast


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