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Home > The Evidence Based Rheumatology Podcast > E29: CIRT and CANTOS - Immunotherapy for Cardiovascular Disease
Podcast: The Evidence Based Rheumatology Podcast
Episode:

E29: CIRT and CANTOS - Immunotherapy for Cardiovascular Disease

Category: Health
Duration: 00:19:58
Publish Date: 2018-11-21 19:51:13
Description:

Double episode this week and then I'll be taking the holidays off.  I decided to combine two trials of immunotherapy for secondary prevention of cardiovascular disease, the CANTOS trial (canakinumab vs. placebo) and the CIRT trial (methotrexate vs. placebo).  It was a good opportunity to debunk both therapies and take a few pot shots at observational trials, "bioplausibility," and surrogate endpoints. Both papers are available on my box account here.

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